The Southeast continues to attract business investment, with South Carolina, North Carolina, and Tennessee benefiting from strong growth driven by talent, infrastructure, and industry momentum. Here are some recent major office moves, headquarters relocations, and workplace upgrades across the Upstate.

Airsys recently opened a $60 million, 60-acre global headquarters campus in the Upstate, establishing its U.S. hub for AI and data center cooling innovation and creating 215 new jobs, with manufacturing expected to begin in Q1 2027.
GE Vernova is scaling energy manufacturing and engineering operations tied to grid modernization and turbine production, including a ~$160 million Greenville facility investment supporting ~600+ jobs.
GNQ Insilico has relocated its corporate HQ and labs from California/Canada to Greenville, launching initial operations at Clemson’s CUBEInC at Prisma Health and later a downtown HQ, as the $500 million biotech AI/quantum company positions for an IPO and future job growth tied to its expanding life sciences platform.
Isuzu North America is investing $280 million to establish a new US production base at a 1 million-sqft facility on 200+ acres in Piedmont, converting it into a truck assembly plant expected to create 700+ new jobs and produce up to 50,000 vehicles annually starting in 2027.
Upstate hospital systems, including Prisma Health ($350 million), Bon Secours (over $27 million), AnMed ($105 million, 50+ jobs), and Novant Health ($132 million), are investing billions in new facilities, expanding beds, ER capacity, and hiring hundreds of workers across the region.
Woodward, Inc. plans a $200 million, 300,000-sqft aerospace manufacturing facility in Greer focused on aircraft spoiler actuation systems, expected to create ~275 jobs with operations beginning in 2027.

Together, these moves represent well over 2,000 new jobs coming to the Upstate, with more announcements rolling in each week. Did your company recently make a big move? Reply to this email and let us know.